Ursula Keller wins “Swiss Nobel” Marcel Benoist Prize- for pioneering work in ultrafast lasers
MUST2022 Conference- a great success!
New scientific highlights- by MUST PIs Wörner, Chergui, and Richardson
FELs of Europe prize for Jeremy Rouxel- “Development or innovative use of advanced instrumentation in the field of FELs”
Ruth Signorell wins Doron prizefor pioneering contributions to the field of fundamental aerosol science
New FAST-Fellow Uwe Thumm at ETH- lectures on Topics in Femto- and Attosecond Science
International Day of Women and Girls in Science- SSPh asked female scientists about their experiences
New scientific highlight- by MUST PIs Milne, Standfuss and Schertler
EU XFEL Young Scientist Award for Camila Bacellar,beamline scientist and group leader of the Alvra endstation at SwissFEL
Prizes for Giulia Mancini and Rebeca Gomez CastilloICO/IUPAP Young Scientist Prize in Optics & Ernst Haber 2021
Nobel Prize in Chemistry awarded to RESOLV Member Benjamin List- for the development of asymmetric organocatalysis
NCCR MUST at Scientifica 2021- Lightning, organic solar cells, and virtual molecules

joint IAP and DCB seminar on Physical Chemistry From Computational Photobiology to the Development of Biomimetic Molecular Devices

Date Do, 15.03.2012 - Do, 15.03.2012
Time 11.15
Speaker Prof. Massimo Olivucci, Laboratory for Computational Photochemistry & Photobiology, Bowling Green State University, OH, USA
Location Universität Bern, Institut für Angewandte Physik, Gebäude exakte Wissenschaften, Hörsaal B116, Sidlerstrasse 5, 3012 Bern
Program During the last few years QM/MM computations based on the CASPT2//CASSCF approach have been employed to investigate spectroscopic and photochemical properties of light-sensitive proteins. In this lecture we will show how the same technology could be used to design light-driven molecular devices. In our lab we are exploring the possibility of designing and synthesizing molecules that could mimic the photoisomerization of the visual pigment Rhodopsin and, in particular its low-temperature photochromism [1]. When embedded in the opsin cavity the Rhodopsin chromophore displays an ultrafast and stereoselective photoisomerization with high quantum yield. In order to design a chromophore displaying a similar efficiency in common solvents we have been looking at diverse alkylated Schiff bases featuring a single isomerizable double bond. In this lecture we show that the indanylidene-pyrroline (NAIP) framework [2-4] provides a computationally and synthetically viable prototype for the development of systems that reproduce the excited state electronic structure and photoisomerization dynamics of Rhodopsin in methanol. We will also show that, on the basis of these studies we have been able to achieve systems that, in perspective, can be used as mechanical or electrostatic switches capable of inverting, reversibly, a ca. 15 D dipole moment upon double bond photoisomerization [5]. [1] Shapiro I., Ryazantsev M. N., Frutos L.-M., Ferré N., Lindh R. & Olivucci M. (2011) J Am Chem Soc 133:3354-3364. [2] Lumento F., Zanirato, V., Fusi, S., Busi, E., Latterini, L., Elisei, F., Sinicropi, A., Andruniów, T., Ferré, N., Basosi, R. & Olivucci, M. (2007) Angew Chem Int Ed Engl 46:414-420. [3] Sinicropi A., Martin, E., Ryasantsev, M., Helbing, J., Briand, J., Sharma, D., Léonard, J., Haacke, S., Cannizzo, A., Chergui, M., Zanirato, V., Fusi, S., Santoro, F., Basosi, R., Ferré, N. & Olivucci, M. (2008) Proc. Nat. Acad. Sci. USA 105:17642-17647. [4] Briand J., Bräm, O., Réhault, J., Léonard, J., Cannizzo, A., Chergui, M., Zanirato, V., Olivucci, M., Helbing, J. & Haacke, S. (2010) Phys Chem Chem Phys 12:3178 - 3187. [5] Melloni A., Rossi Paccani, R., Donati, D., Zanirato, V., Sinicropi, A., Parisi, M. L., Martin, E., Ryazantsev, M., Ding, W. J., Frutos, L. M., Basosi, R., Fusi, S., Latterini, L., Ferré, N. & Olivucci, M. (2010) J Am Chem Soc 132:9310-9319.
Download (75 KB)
(75 KB)
NCCR MUST Office : ETHZ IQE/ULP-HPT H3 | Auguste-Piccard-Hof 1 | 8093 Zurich | E-Mail
The National Centres of Competence in Research (NCCR) are a research instrument of the Swiss National Science Foundation