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05.09.2022 - 09.09.2022, Iseolago hotel, Iseo, Italy.

News

MUST2022 Conference- a great success!
New scientific highlights- by MUST PIs Wörner, Chergui, and Richardson
FELs of Europe prize for Jeremy Rouxel- “Development or innovative use of advanced instrumentation in the field of FELs”
Ruth Signorell wins Doron prizefor pioneering contributions to the field of fundamental aerosol science
New FAST-Fellow Uwe Thumm at ETH- lectures on Topics in Femto- and Attosecond Science
International Day of Women and Girls in Science- SSPh asked female scientists about their experiences
New scientific highlight- by MUST PIs Milne, Standfuss and Schertler
EU XFEL Young Scientist Award for Camila Bacellar,beamline scientist and group leader of the Alvra endstation at SwissFEL
Prizes for Giulia Mancini and Rebeca Gomez CastilloICO/IUPAP Young Scientist Prize in Optics & Ernst Haber 2021
Nobel Prize in Chemistry awarded to RESOLV Member Benjamin List- for the development of asymmetric organocatalysis
NCCR MUST at Scientifica 2021- Lightning, organic solar cells, and virtual molecules
#NCCRWomen- NCCR MUST celebrates 50 years women’s right to vote in Switzerland

Imaging Proteins with X-ray Free-Electron Laser Pulses

Chapman
Date Mi, 12.10.2011 - Mi, 12.10.2011
Time 16:45
Speaker Henry Chapman, Center for Free-Electron Laser Science, DESY Hamburg, Germany
Location ETH Hönggerberg HPV G4
Program The ultrafast pulses from X-ray free-electron lasers (FELs) are of high enough intensity and of sufficiently short duration that individual single-shot diffraction patterns can be obtained from a sample before significant damage occurs at the atomic scale. We have applied this “diffraction before destruction” method to determine the molecular structures of proteins that cannot be grown into large enough crystals or are too radiation sensitive for conventional X-ray crystallography. Using the Linac Coherent Light Source, the world’s first hard X-ray FEL, we recorded millions of diffraction patterns from a flowing stream of protein nanocrystals of the photosystem I complex and other proteins. Our measurements show that sample destruction at high resolution can be avoided with pulses of 30 fs or shorter.
We aim to push this technique to smaller and smaller samples – all the way down to the single molecule.

Host: Jürg Osterwalder

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Link
Zurich Physics Colloquium
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