Ursula Keller wins “Swiss Nobel” Marcel Benoist Prize
Farewell: the NCCR MUST ended 
MUST2022 Conference
New scientific highlights
FELs of Europe prize for Jeremy Rouxel
Ruth Signorell wins Doron prize
New FAST-Fellow Uwe Thumm at ETH
International Day of Women and Girls in Science
New scientific highlight
EU XFEL Young Scientist Award for Camila Bacellar,
Prizes for Giulia Mancini and Rebeca Gomez Castillo
Nobel Prize in Chemistry awarded to RESOLV Member Benjamin List
Hans Jakob Wörner invited to give the „New Horizons Solvay Lectures” 
Unusual keynote talk at an international scientific conference
NCCR MUST at Scientifica 2021Fast bioimaging with an X‐ray laser
| Date | Fr, 20.04.2012 | |
| Time | 11:15 am | |
| Speaker | John C.H.Spence, ASU Physics and LBNL, USA | |
| Location | PSI, WHGA/001 | |
| Program | P S I C o l l o q u i u m I will review our* recent experiments with the first hard X‐ray laser at SLAC near Stanford, the LCLS. These have included snap‐shot imaging from membrane protein nanocrystals and viruses, and the first pump‐probe experiments on Photosystem 1 ‐ ferredoxin using a liquid jet sampledelivery system of novel design. Our aim is to record movies of molecular machines at work, using femtosecond X‐ray pulses so brief that they terminate before radiation damage commences. New phasing methods for protein nanocrystals and the extraction of structure factors by our Monte‐Carlo method will be reviewed. Recent work using angular correlation functions to recover molecular images from the correlated fluctuations in snap‐shot diffraction patterns from many randomly‐oriented molecules in solution will also be outlined. The prospects for dynamic snapshot chemical imaging using mixing jets will also be described, and a new method based on the Kapitza‐Dirac effect which uses a laser as a Zernike phase plate for electron microscopy. Finally, we consider the prospects for using fast electron beam pulses instead of X‐rays for molecular movies. * Chapman et al Nature 470, 73 (2011). Spence et al Rep. Prog. Phys. (2012). Fromme and Spence, Curr. Opin. Struct. Biol. 21, 509 (2011). |
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| Download |  Flyer (77 KB) |
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| Link | Home Site | |
