Ursula Keller wins “Swiss Nobel” Marcel Benoist Prize- for pioneering work in ultrafast lasers
MUST2022 Conference- a great success!
New scientific highlights- by MUST PIs Wörner, Chergui, and Richardson
FELs of Europe prize for Jeremy Rouxel- “Development or innovative use of advanced instrumentation in the field of FELs”
Ruth Signorell wins Doron prizefor pioneering contributions to the field of fundamental aerosol science
New FAST-Fellow Uwe Thumm at ETH- lectures on Topics in Femto- and Attosecond Science
International Day of Women and Girls in Science- SSPh asked female scientists about their experiences
New scientific highlight- by MUST PIs Milne, Standfuss and Schertler
EU XFEL Young Scientist Award for Camila Bacellar,beamline scientist and group leader of the Alvra endstation at SwissFEL
Prizes for Giulia Mancini and Rebeca Gomez CastilloICO/IUPAP Young Scientist Prize in Optics & Ernst Haber 2021
Nobel Prize in Chemistry awarded to RESOLV Member Benjamin List- for the development of asymmetric organocatalysis
NCCR MUST at Scientifica 2021- Lightning, organic solar cells, and virtual molecules

Shaping the future of biophotonics: applying novel light fields

Date Di, 05.07.2011 - Di, 05.07.2011
Time 10.15
Speaker Prof. Dr. Kishan Dholakia, FRSE, School of Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Scotland
Location Universität Bern, Institut für Angewandte Physik, Gebäude exakte Wissenschaften, Hörsaal B116, Sidlerstrasse 5, 3012 Bern
Program Light is incredible. 2010 marked the fiftieth anniversary of the laser. Its impact has been immense across all of the Sciences with an array of ground-breaking studies. Laser light typically emanates in what is termed a standard Gaussian beam. As we explore light propagation we see this is a “basic” solution and indeed is the form of laser light most used today. However it is becoming critically apparent to a wide range of science that this basic form of light propagation is insufficient for numerous applications and indeed that our very understanding of the propagation and application of light needs to be re-addressed particularly for turbid or complex media. Very surprising and startling results are possible. By engineering and exploiting the phase and amplitude characteristics of light – optical sculpting – we may provide a major breakthrough of how light actually propagates in a variety of media. This will lead to us many exciting questions: how might we locally overcome the diffraction limit in the far field? How might we overcome the resolution criteria in focusing? How do we obtain an optimal beam for trapping in a turbid or complex media? How might we even explore ‘sub-diffractive’ nanosurgery or multiphoton imaging of cells and tissue?
In this talk, I will describe some recent work where we apply exquisite control over the phase and amplitude of light to yield some very surprising results. By performing in situ adaptive optics, optical trapping of nanoparticles and microparticles through highly turbulent media becomes a reality. This opens up new vistas in precision measurements in complex media and potentially studies in vivo.
Separately, cell transfection is an important area of ultrafast biophotonics. The application of such ultrashort pulses from a high repetition rate laser creates a low density free electron plasma that photochemically disrupts the cell membrane in a transient fashion.
Excitingly the method allows transfer of macromolecules and drugs as well as nanoscopic particles into various cells and is an emergent area in Nanobiophotonics. I will describe our latest work in this field emphasising new physics of using both ‘non-diffracting’ light beams and far-field ‘sub-diffraction’ beam shaping to instigate transfection.
Download (75 KB)
(75 KB)
NCCR MUST Office : ETHZ IQE/ULP-HPT H3 | Auguste-Piccard-Hof 1 | 8093 Zurich | E-Mail
The National Centres of Competence in Research (NCCR) are a research instrument of the Swiss National Science Foundation